13 TV Shows Where the Cast Changed Drastically

NO ONE IS SAFE ON “GREY’S ANATOMY”

Of the doctors on “Grey’s,” there are only four remaining from the show’s very first season: Ellen Pompeo as Meredith Grey, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, and James Pickens Jr. as Richard Webber. Five other actors started on season one but later left. Isaiah Washington left during season three, T.R. Knight left during season five, Katherine Heigl left during season six, Sandra Oh left during season 10, and Patrick Dempsey left during season 11. Other doctors have come and stayed, while others have come and gone, but one thing is for certain, the cast doesn’t look the same.